Natural Product Communications, vol: 12,12 (2017)

A new cytotoxic polyacetylenic alcohol from a sponge Callyspongia sp.

Balansa W., Trianto A., De Voogd N.J., Tanaka J.

Abstract

A new cytotoxic polyacetylenic alcohol 1 was isolated from an Indonesian sponge Callyspongia sp. The structure of compound 1 was elucidated by spectral analyses and by applying modified Mosher’s method. Compound 1 killed the cultured NBT-II rat bladder carcinoma cells at 5 and 10 μg/mL.

Keyword: Callyspongia; Cytotoxicity.; Polyacetylene; Sponge

DOI

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